Precipitation of Acetaminophen in Supercritical Carbon Dioxide 


Vol. 10,  No. 4, pp. 215-220, Dec.  2004


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  Abstract

Micronized acetaminophen was precipitated from ethanol solution using supercritical CO2 as antisolvent. A coaxial nozzle was used to introduce the supercritical CO2 and the acetaminophen/ethanol solution. The effects of pressure, temperature, CO2 flow rate and solvent flow rate were studied in the constant pressure and temperature condition. The particle size and morphology were influenced by the variations of precipitation condition. The particle size and morphology were analyzed with scanning electron microscopy.

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  Cite this article

[IEEE Style]

C. S, O. K, K. H, "Precipitation of Acetaminophen in Supercritical Carbon Dioxide," Clean Technology, vol. 10, no. 4, pp. 215-220, 2004. DOI: .

[ACM Style]

Choi S, Oh K, and Kim H. 2004. Precipitation of Acetaminophen in Supercritical Carbon Dioxide. Clean Technology, 10, 4, (2004), 215-220. DOI: .

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pISSN : 1598 - 9712
eISSN : 2288 - 0690

한국연구재단 등재학술지