Solubility of Triclosan in Supercritical Carbon Dioxide and its Application to Micronization Process 


Vol. 14,  No. 3, pp. 153-159, Sep.  2008


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  Abstract

The solubility of triclosan, an anti-acne agent was measured in supercritical carbon dioxide (scCO2) with a variable volume view cell at 313.15, 323.15, and 333.15 K and at pressures between 10 and 40 MPa. We successfully correlated triclosan solubility in scCO2 using the quasi-chemical nonrandom lattice fluid (QLF) equation of state. Triclosan was micronized using the rapid expansion of supercritical solutions (RESS) process. The effects of temperature and pressure on particle size were investigated using phase behavior data and correlated results from the QLF model.

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  Cite this article

[IEEE Style]

S. MS and K. H, "Solubility of Triclosan in Supercritical Carbon Dioxide and its Application to Micronization Process," Clean Technology, vol. 14, no. 3, pp. 153-159, 2008. DOI: .

[ACM Style]

Shin MS and Kim H. 2008. Solubility of Triclosan in Supercritical Carbon Dioxide and its Application to Micronization Process. Clean Technology, 14, 3, (2008), 153-159. DOI: .

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pISSN : 1598 - 9712
eISSN : 2288 - 0690

한국연구재단 등재학술지